Wednesday, September 12, 2012

The changes in triglyceride levels in people taking Prednisone

There are a number of drugs in regular use that can trigger a change in your levels of triglycerides, LDL and HDL cholesterol levels. When the level falls, this is a potential benefit, reducing the risk you will develop cardiovascular disease. It can be a problem when you are already taking drugs to reduce your cholesterol levels, and this represents the perfect example of why you should always take advice before you take two different drugs at the same time. Prednisone is one of the drugs with the reverse effect. It stimulates your appetite and, if you increase your intake of less healthy foods, you will see a fairly rapid increase in triglyceride and cholesterol levels, sometimes within two weeks. Why should this matter? About 20% of the adult population lives with elevated triglyceride levels and does not immediately fall ill as a result.
The triglycerides are a type of lipid circulating in the blood to carry energy to where it's needed. Under normal circumstances, the triglycerides are stored by converting them into fat at the point of need. Unfortunately, Prednisone and the other corticosteroids actually changes the sites where the fat is deposited creating the rather distinctive "look". In addition, the higher levels of lipids increases the rate at which platelets are deposited on the walls of your blood vessels. Over time, this causes artherosclerosis, a hardening of the arteries which can be the first danger sign for a stroke or heart attack.
If you develop high levels of triglycerides and the drug is no longer needed, you simply taper down and stop taking it. Alternatively, you can reduce the dosage of Prednisone to the lowest level needed to give you effective treatment or, if you are taking the drug for breathing problems, switch to a spray which reduces the side effect. Finally, you can maintain the dosage but add a statin or some other drug that reduces the amount of cholesterol circulating in your blood. The one thing you should not do is ignore the problem. This can very rapidly produce lipid levels indicating danger to your health.

Monday, September 10, 2012

The accidental poisoning of children and Carisoprodol

There's a fascinating difference in responses when people are told how to run their own homes. Some take the rational approach of listening politely and then making a decision based on common sense. But others are angry the moment the state or, worse, the federal government tries to interfere with "private" matters. Take gun controls as an example. You can't tell most NRA members about how to store their weapons safely. Start talking about installing safes or other places where guns and ammunitions can be kept out of children's hands, and you may justly fear for your own safety.
It's exactly the same when you start talking about installing lockable cabinets for the storage of prescription drugs. Although the risk of a shooting is probably lower, the chances of persuading parents to ensure their children cannot get access to the drugs and treat them as if they were sweeties, are low.
Even when local news media carry stories about a neighbor's child, the reaction seems to be blame of the parent without looking inside their own glass houses.
Why is this a problem? In 2011, the American Association of Poison Control Centers published a report on the scale of pediatric poisoning. That's your children being poisoned. Between 2001 and 2008, almost 550,000 children ended in the ERs with medication poisoning. Of these, more than 75% were so seriously injured, they were hospitalized with amazing medical bills handed to families as their reward for not preventing access. Those with health insurance don't have to pay the price of their own negligence as they are, of course, protected.
When parents can see that the packaging of painkillers, heart medications and muscle relaxants like Carisoprodol are not childproof, they should immediately take greater care. Since we cannot rely on manufacturers to supply flow restrictions on liquid containers or dispensing systems that only allow one pill at a time, locking the drugs away is the only safe option. This raises the question of whether you are keeping your children safe when you have to dash to the ER and spend hours worrying as to whether you child will live due to your failure with powerful drugs like Carisoprodol pills.

Monday, September 3, 2012

Cialis and men with heart disease

When you are diagnosed as having high blood pressure, this is one of the early symptoms suggesting a higher risk of heart disease. If you also have erectile dysfunction, it suggests the damage to your blood vessels may be quite advanced. The difficulty is the so-called potentiating effect. Cialis is one of the PDE5 inhibitors and, although it's designed to be reasonably specific to the penile artery, it does have a general effect on the arterial system and does, in its own right, lower your blood pressure. If you are also taking drugs to reduce your blood pressure, the combination in a small percentage of men can produce rapid and dangerous drops. This needs careful management to ensure you do not come to harm. So always tell your doctor or pharmacist if you are also taking ACE inhibitors, diuretics or betablockers.
This leads to a more general need to provide counseling to men who are diagnosed with symptoms, including erectile dysfunction, showing a high risk of heart disease. The quality of life is directly affected by whether sexual activity is possible. If men fail to achieve consistent levels of satisfaction, it's not uncommon to find depression follows. Many of the antidepressive medications do cause loss of libido and other sexual problems, so this becomes a vicious circle in which men's self-esteem and sense of self-worth are seriously damaged.
Cialis is an excellent drug whether taken as needed or once-daily. But men need to have a very clear understanding of how to get the best results. Only then can they remain positive. So they need guidance on reducing alcohol intake and, if they have not already done so, quitting smoking. Maintaining at least one hour after taking the as-needed version of Cialis is desirable. This waiting time should be extended to two hours if a meal with a high fat content has been eaten or significant alcohol has been consumed. There then needs to be discussion of what sexual stimulation to engage in and reinforcement of the need to try several difference positions and/or situations before giving up.

Saturday, September 1, 2012

Cialis and the demand among single men

Some men never form permanent relationships and essentially live solitary lives, making friends where possible. As they age within the community, there's a tendency not to leave the home so often to socialize. This reinforces the loneliness and, quite commonly, leads to some level of depression. Other men find their relationships brought to an end, whether by separation, divorce or the death of the partner. Involuntarily, this forces the men into a decision on returning to a social life outside the home, or just staying home to wait for the end. Ironically, one of the best things that can happen to a single man is to move into a community of older people. This may be in separate homes with central services provides by a management company, or it may be a room in a home for the elderly. Although this is a loss of independence which may threaten self-esteem, it also represents an opportunity to meet other people. On occasion, men who remain sexually active can find themselves in demand from single women in the same or nearby communities. At times like this, Cialis becomes the reliable support to rejoining the world of sexual activity.
In this, the quality of the neighborhood is the key to whether the single man prospers or succumbs to depression. Some cultures are very unwelcoming to the old. Like annoying children, they are expected to stay out of sight. In such environments, the elderly feel trapped in their own homes. However, some neighborhoods are broadly supportive and open to all. For example, a recent survey in some Australian states discovered strong pub cultures in which men of all ages mixed and, in both positive and passive terms, offered support to older members of the community. This actually has more general health implications because older men who continue to drink beer on a regular basis are over overweight and inactive. This increases the risk factors of heart disease. Fortunately, the Australian women of all ages know where to find the men and, if they are looking for a partner can bring the Cialis with them to ensure a good result.

Prednisone and managing the withdrawal symptoms

Because this drug produces high levels of cortisone in the blood stream, your adrenal gland slows down and ultimate stops working. This ultimate loss of natural production can be delayed either by taking a significantly lower dose over the relevant period of time, or taking the prescribed dose every other day. This allows the artificial level of cortisol to fall and encourages the adrenal gland to maintain some production. But if the evidence suggests the adrenal gland has stopped, it's actually dangerous to stop taking Prednisone suddenly. The almost inevitable symptoms are an initial feeling of nausea, followed by a sudden and severe feeling of tiredness, your body will start to ache with particular pain in the joints. If the gland fails to start, you will find yourself increasingly weak. Needless to say, this turns you from an active individual into a bedridden invalid in a few days.
To reduce the likelihood of adverse effects, you have to slowly reduce the daily dosage. This slow reduction will take weeks if not months. The actual length of time will vary depending on the disease being treated, how long you have been taking the drug, the dosage, and your general state of health. There are different approaches. The most popular calls for alternating higher and lower doses over the first weeks, then dropping down to lower doses every day. Many find it better to reduce the individual doses, but take them spaced evenly through the day. If you begin to feel joint pain, you take one of the nonsteroidal anti-inflammatory drugs to ease you through. If your skin has been affected by the Prednisone, stay out of the sun or, if this cannot be avoided, use sunscreen and keep as much of your body covered as possible. You should also cut down on food rich in vitamin D.
If you find the withdrawal symptoms are growing worse, you are tapering too fast. Never ignore this. Always discuss the symptoms with your regular doctor and change the dosages and the times you take them until you are comfortable again.